Yellaggird Subbarao

Yelpprogram Subbaraov (Telugu: యెల్లప్రగడ సుబ్బారావు) (12 January 1895-9, August 1948) was an Indian scientist who contributed significantly to the treatment of cancer. He had spent most of his career in America but despite this, he remained a foreigner there and did not take the green card, although during World War II he had led some of the most important medical research in America. Despite the separation of adenocinine typhosphate (ATP), they were not posted as a professor at Harvard University.

Early life and education

Yellaggad Subbarao was born in a Telugu Niyogi Brahmin family in Bhimavaram, Madras Presidency (now West Godavari district, Andhra Pradesh). During his schooling in Rajmundari, he had to spend a lot of hard time (due to the deaths of close relatives from close relatives). Eventually, he passed his matriculation examination from the Hindu High School in the third attempt. They had been suffering from diarrhea for quite a long time and this disease came under control after a lot of treatments. Dr. Achanta Lakshmipati, a well-known Ayurvedic doctor of that time, treated them as they got cured. He passed the Intermediate examination from Presidency College and entered Madras Medical College, where his education was spent by friends and Kasturi Suryanarayan Murthy (with whom his daughter was later married). In honor of Mahatma Gandhi's appeal to the boycott of British goods, he started wearing khadi's surgical costume and due to this he got his surgery professor M. C. Bradfield suffered the heartburn. Although he had obtained good marks in his written examination, but due to this episode he was given a full MBBS. LMS instead of degree The certificate had to be satisfied.

Subbarao tried to enter the Madras Medical Service, but he did not get any success in this. He then took a job as the lecturer of anatomy in Dr. Lakshmipathy Ayurvedic College, Madras. They were so fascinated by the medical powers of Ayurvedic medicines that they gathered in research to get Ayurveda recognized at the modern level.

An American doctor, who was visiting India on Rockefeller Scholarship, changed their mind with a coincidence meeting with them. Subbarao left for America with promises of support of Malladi Satyalinga Naikar Sansthan and financial help given by his father-in-law. They arrived in Boston on October 26, 1922. Career in America

After receiving a diploma from Harvard Medical School, he joined the junior faculty as a member at Harvard. With Cyrus Fiske, he developed a method to assess the quantity of phosphorus in the body fluids and tissues. In the muscular activity, he discovered himself in 1930 in biochemistry science textbook by searching for phosphokrietine and adenosine triphosphate (ATP). He also got his PhD degree in the same year.

Due to not receiving a regular faculty at Harvard, it was joined by the Lederrele Laboratory, which was part of the American Sainamide at that time (acquired by Wyeth in 1994, now with Pfizer). In Ledrele, he researched the method of synthesis of folic acid (vitamin B 9), based on the work of having Lucy Wills's folic acid as a protective component against anemia. Taking forward the work done on his folic acid, he synthesized the world's first chemotherapy agent (anti-cancer claim) methotrexate, using the folic acid in the cereal form, which is still in broad progress. He also discovered diethylcarbazepine (hepatrazan), which was used by the World Health Organization in elephantiasis (filaria). Working in the supervision of Subbarao, Benjamin Dugger discovered the world's first tetracycline antibiotic aromacin in 1945. This discovery was the result of the most distributed scientific experiment of that time. The American soldiers returning to the end of World War II were instructed to collect soil samples wherever they were and bring them to the test of possible anti-bacterial agents produced by natural soil fungus in the Laboratory of Laderley. / p> Delay in recognition and acknowledgment

Subbarao's memory was hidden due to the achievements of others and the failure to promote their own interests. A patent lawyer was surprised to see that he did not take any steps to add his name to his work, which the scientists regularly do throughout the world. He never allowed the Press to be interviewed for the interview nor visited the academies to share the applause nor did he ever go on lecture tour.

His associate, George Hitchings, who won the Nobel Prize in Medicine with Eliëan Gertrud in 1988, said, "Nucleotides separated by Subbarao have been searched again by other crew after a few years, because Fiske's manifestation Due to jealousy, Subbarao's contribution did not see the light of day. "

In honor of them, a fungal subbromasis was named Splenadence by the American Sainmid.

Writing in the Argosi ​​magazine of April, 1950, Doron K. Antrim wrote - "You have probably never heard about Dr. Yellapragada Subbarao, probably because he lived so that you can survive today and live a good life because he lived, now you can live a long life."

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